Vertex Pharmaceuticals’ stock price (VRTX) fell in the intraday levels, with negative pressure from the 50-day SMA, amid the dominance of the downward correctional trend in the short term, with negative signals from the RSI after reaching overbought levels. 

Therefore we expect more losses for the stock, targeting the first support at $387.40, provided it settles below the resistance of $407.00. 

Trend forecast: Bearish