The Australian dollar fell slightly against most currencies as concerns about the Omicron eased, amid improved risk-appetite in assets such as commodities, currencies and stocks.
Trading is calm during this week as global markets are now preparing for the end of 2021.
A study on cases infected with the omicron variant suggests lower risk of hospitalization and death compared to the delta variant.
Many countries have tightened their precautionary measures amid the holidays season, but none re-imposed full lockdown.
However, the markets are focused on the growing numbers of infections in the UK and several other European countries.
As of 17:35 GMT, AUD/USD fell 0.1% to 0.7229, after hitting a high of 0.7265, and a low of 0.7219.